Visiopharm's popular stereology software provides unbiased stereological estimates of numbers, lengths, areas, and volumes on images captured on microscopes or virtual slides. The stereology module is driven by newCAST™ which was developed in close collaboration with world-leaders in the field and is the most comprehensive, robust, user-friendly and versatile stereological system available today.

A DESIGN BASED STEREOLOGY SOLUTION

Designed based stereology software, ensures unbiased estimates of structural information (volume, area, length, and number) in 3-D obtained from 2-D tissue sections. Stereology (newCAST) from Visiopharm is a complete, well-documented solution that has been cited in over 500 publications just since 2010.

A COMPLETE STEREOLOGY TOOLBOX

The Stereology module provides a powerful stereology toolbox to accurately estimate relevant end-points using points, lines, counting frames; physical and optical disectors and fractionators; virtual planes; local estimators including nucleator and rotator, and a unique unbiased method for handling artificial edges.

COMBINE PROBES FOR MORE QUANTITATIVE POWER

The Stereology module has a comprehensive selection of stereological probes that can be combined to allow for simultaneous analysis of several end-points. Modern stereological methods introduce a need for efficient handling of local thickness measurement and guard zones at artificial edges for calculation of exact sampling probabilities. Local thickness measurement and guard zone handling are seamlessly integrated into Stereology.

AN ORGANIZED, INTUITIVE WORKFLOW

Sample, count, document, calculate, publish-it's that simple. Stereology will support users through each step of the process yielding powerful results of unbiased estimates that will meet or exceed the high standards of leading scientific journals for publication.

INCREASE SAMPLING EFFICIENCY

The Stereology module can be expanded with The Proportionator™ which greatly increases sampling efficiency since practically all fields of view will contain the feature of interest. A comparative study has shown that the Proportionator™ was twice as fast as normal meander sampling and in combination with Visiopharm's Autodisector™, it became three times faster (Keller et al. 2013, Journal of Microscopy, 251: 68–76)!

AUTOMATED PHYSICAL FRACTIONATOR

Visiopharm's patented Autodisector™ makes it possible to work fast and efficiently with the Physical Disector principle, and thereby reduce or eliminate frequently occurring practical problems due to section shrinkage, staining penetration, opaque tissues, and large objects.

WHOLE SLIDE IMAGES, MICROSCOPES, AND MORE

Visiopharm provides systems fully configured with all hardware components, but we can also help you to retrofit to your existing system, and are fully compatible with leading hardware brands. Visiopharm Stereology software is designed to facilitate every step in the workflow from prepared tissue sections to delivering scientifically valid, quantitative end-points that reflect important tissue properties.

DEVELOPED AND TESTED BY LEADING EXPERTS

Visiopharm's newCAST™ is the backbone of Stereotopix™ and originates from the stereology epicenter of Aarhus University, Denmark, developed and tested with Profs. H.J. Gundersen and J.R. Nyengaard. New methods and tools for Stereotopix™ are routinely developed, implemented and tested in close collaboration with the Stereology Research Laboratory.


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