Visiopharm: HT Whole Slide Stereology™




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newCAST Whole Slide Stereology™

HT Whole Slide
Stereology™

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Whole Slide Stereology

HT Whole Slide Stereology™

A stereology toolbox for High Through-put analysis

Stereology software developed in close collaboration with inventors and of modern design-based stereology, Prof. Hans Jørgen G. Gundersen and Prof. Jens R. Nyengaard from the Stereology Research Laboratory, University of Aarhus, Denmark.

High Through-put Whole Slide Stereology software provides a complete set of well-documented stereology tools allowing the researcher to accurately estimate relevant end-points through the use of:

Points, lines, counting frames
Physical disector and fractionator
Local estimators - nucleator and rotator
Unique, unbiased method for handling artificial edges

All probes are scientifically well-documented and have been rigorously tested by Prof. Hans Jørgen G. Gundersen and Prof. Jens R. Nyengaard from the University of Aarhus, Denmark.

Point probe for volume estimation

Counting frame for number and length estimation

Line probe for surface estimation

Nucleator for local vol/area estimation

Rotator probe for local vol estimation

Automated Physical Disector

HT Whole Slide Stereology software makes it possible to work fast and efficiently with the physical fractionator principle by automating the most time-consuming aspects of the physical disector.

The patented Autodisector module in the HT Whole Slide Stereology software allows for automated alignment of paired tissue sections and unattended sampling in the matched disector pairs. The sampled disector pairs are stored in the system database as corresponding digital images and the whole sampling can be accessed from remote workstations. This makes it possible for a single imaging station to serve several researchers who can download their studies to remote analysis stations.

Proportionator - efficient sampling

The proportionator is the most efficient unbiased stereological sampling method. The proportionator samples with Probability Proportional to Size (PPS), which means that fields of view are not sampled with the same probability. Rather, fields of view with high content of the feature in question, has a higher (known) probability of being selected. The principle improves efficiency of the estimation process up to 25 times as empty fields of view become rare events.

The Proportionator™ sampling method can be combined with all available probes in the HT Whole Slide Stereology software.

With the Visiopharm HT Whole Slide Stereology software, it is possible to design the optimal setup for research projects, combining well-documented sampling strategies and stereological probes with an increased flexibility.

All collected data (sampling parameters, probe data, and analysis results) are seamlessly recorded for calculation of the final results, and are immediately available for export to MS Excel.

Technical features HT Whole Slide Stereology Package

What is Whole Slide Stereology?

What is Stereology?

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